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Validated Breakthrough Technology

 
Metabolism is the single largest factor that dictates our daily caloric needs, varying from person to person and from time to time. The Academy of Nutrition and Dietetics recommends the tracking of metabolism with gold standard indirect calorimetry, which requires accurate measurement of a person’s consumed O2 and produced CO2 rates in breath. Breezing’s patented device captures and processed the breath O2 and CO2 concentrations, in combination with other pulmonary measurements, to achieve accurate metabolic rate reading.

Diagram of case study 1 showing 333% improvement in weight and BMI reduction, 70% better adherence to healthy behaviors, and 3 to 6 times more improvement in specific risk factors

Diagram of case study 2 showing the Breezing mobile app

Click this link: Published on the Global Journal of Obesity,
Diabetes, and Metabolic Syndrome

Click this link: Published in collaboration with Mayo Clinic

Clinical Studies

 
Clinical case studies in collaborations with the Mayo Clinic, the Pulmonary and Sleep Medicine Associates, the University of Arizona, and Arizona State University have proven the use of Breezing leads to efficient personalized weight management.

CASE 1 – Breezing Accuracy Validation

Based on clinical studies and laboratory tests, Breezing’s accuracy is ~100% with 95% confidence intervals compared to the gold standard reference methods.  The findings of the clinical studies are summarized below.

  • Breezing accurately measures, O2, CO2, and REE, with results concurring with the Douglas Bag Method, with p < 0.0001
  • The study validates Breezing as an accurate tool for assessing metabolic parameters
  • Breezing helps healthcare providers assess patient’s metabolic health and develop personalized weight management programs with better clinical outcomes

CASE 2 – Effect of Mobile Indirect Calorimeter on Weight Management

In a published clinical study, patients treated with the Breezing device experienced twice as much weight loss, and 70% better adherence to healthy behaviors, with significant improvements in risk factors for Type II diabetes including HbA1C, cholesterol, and blood pressure.  The  clinical studies are summarized below.

  • Adding RMR to weight loss program using mobile Breezing resulted in greater weight loss; improved HDL cholesterol and greater adherence to health monitoring
  • It facilitated more comprehensive use of calorie counter app, including calorie intake tracking, activity tracking, weight tracking and sharing functions
  • Breezing provides tailored, precise, and accurate information to patients for health monitoring and improvement

CASE 3 – Metabolism Calculation vs. Actual Measurement

While calculations provide population average RMR, a comparison study between RMR calculated by the Mifflin St-Jeor predictive equation (MSJE) and RMR measured by the indirect calorimetry method with Breezing showed that the calculated values can under- and over-estimate the actual RMR by 950 and 660 kCal per day, respectively.  The following captures the Case 3 clinical studies findings:

  • Breezing is a much easier method to use assess RMR and the measurement using Breezing should be practiced for clinical use

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